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Breast cancer is cancer that develops from breast tissue. Risk factors for developing breast cancer include being female, obesity , a lack of physical exercise, alcoholism , hormone replacement therapy during menopause , ionizing radiation , an early age at first menstruation , having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer.
The balance of benefits versus harms of breast cancer screening is controversial. A Cochrane review found that it was unclear if mammographic screening does more harm than good, in that a large proportion of women who test positive turn out not to have the disease. Outcomes for breast cancer vary depending on the cancer type, the extent of disease , and the person's age. Breast cancer most commonly presents as a lump that feels different from the rest of the breast tissue.
Another symptom complex of breast cancer is Paget's disease of the breast. This syndrome presents as skin changes resembling eczema; such as redness, discoloration or mild flaking of the nipple skin. As Paget's disease of the breast advances, symptoms may include tingling, itching, increased sensitivity, burning, and pain.
There may also be discharge from the nipple. Approximately half the women diagnosed with Paget's disease of the breast also have a lump in the breast. Inflammatory Breast Cancer presents with similar effects. The visual effects of Inflammatory Breast Cancer is a result of a blockage of lymph vessels by cancer cells. This type of breast cancer is seen in more commonly diagnosed in younger ages, obese women and African American women. As inflammatory breast cancer does not present as a lump there can sometimes be a delay in diagnosis.
In rare cases, what initially appears as a fibroadenoma hard, movable non-cancerous lump could in fact be a phyllodes tumor. Phyllodes tumors are formed within the stroma connective tissue of the breast and contain glandular as well as stromal tissue. Phyllodes tumors are not staged in the usual sense; they are classified on the basis of their appearance under the microscope as benign, borderline or malignant. Malignant tumors can result in metastatic tumors— secondary tumors originating from the primary tumor that spread beyond the site of origination.